Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | CAR_HPX |
| Enrichment Score (ES) | -0.33294815 |
| Normalized Enrichment Score (NES) | -1.7090734 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.08528694 |
| FWER p-Value | 0.303 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | UGT2B11 | NA | UGT2B11 Entrez, Source | UDP glucuronosyltransferase 2 family, polypeptide B11 | 2150 | 1.655 | -0.0342 | No |
| 2 | AGT | NA | AGT Entrez, Source | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 2542 | 1.486 | -0.0084 | No |
| 3 | CDO1 | NA | CDO1 Entrez, Source | cysteine dioxygenase, type I | 2583 | 1.467 | 0.0298 | No |
| 4 | CPS1 | NA | CPS1 Entrez, Source | carbamoyl-phosphate synthetase 1, mitochondrial | 3203 | 1.238 | 0.0405 | No |
| 5 | TFR2 | NA | TFR2 Entrez, Source | transferrin receptor 2 | 3731 | 1.073 | 0.0502 | No |
| 6 | HGFAC | NA | HGFAC Entrez, Source | HGF activator | 3777 | 1.059 | 0.0772 | No |
| 7 | PON3 | NA | PON3 Entrez, Source | paraoxonase 3 | 5334 | 0.654 | 0.0377 | No |
| 8 | LPA | NA | LPA Entrez, Source | lipoprotein, Lp(a) | 5693 | 0.579 | 0.0403 | No |
| 9 | PAH | NA | PAH Entrez, Source | phenylalanine hydroxylase | 5957 | 0.535 | 0.0451 | No |
| 10 | APOA1 | NA | APOA1 Entrez, Source | apolipoprotein A-I | 6128 | 0.507 | 0.0525 | No |
| 11 | APCS | NA | APCS Entrez, Source | amyloid P component, serum | 7147 | 0.382 | 0.0255 | No |
| 12 | SERPINF2 | NA | SERPINF2 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 7681 | 0.327 | 0.0148 | No |
| 13 | AQP9 | NA | AQP9 Entrez, Source | aquaporin 9 | 8240 | 0.282 | 0.0019 | No |
| 14 | RBP4 | NA | RBP4 Entrez, Source | retinol binding protein 4, plasma | 8284 | 0.278 | 0.0079 | No |
| 15 | ITIH3 | NA | ITIH3 Entrez, Source | inter-alpha (globulin) inhibitor H3 | 8315 | 0.276 | 0.0142 | No |
| 16 | HPX | NA | HPX Entrez, Source | hemopexin | 8685 | 0.249 | 0.0074 | No |
| 17 | SDS | NA | SDS Entrez, Source | serine dehydratase | 9038 | 0.228 | 0.0007 | No |
| 18 | C4BPB | NA | C4BPB Entrez, Source | complement component 4 binding protein, beta | 9429 | 0.207 | -0.0080 | No |
| 19 | HPD | NA | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 9774 | 0.189 | -0.0155 | No |
| 20 | MBL2 | NA | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 9779 | 0.189 | -0.0106 | No |
| 21 | CYP2E1 | NA | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 10317 | 0.164 | -0.0258 | No |
| 22 | ARG1 | NA | ARG1 Entrez, Source | arginase, liver | 10376 | 0.161 | -0.0236 | No |
| 23 | ALDOB | NA | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 10612 | 0.151 | -0.0282 | No |
| 24 | CFHR2 | NA | CFHR2 Entrez, Source | complement factor H-related 2 | 10851 | 0.139 | -0.0331 | No |
| 25 | CPB2 | NA | CPB2 Entrez, Source | carboxypeptidase B2 (plasma, carboxypeptidase U) | 11051 | 0.130 | -0.0369 | No |
| 26 | LECT2 | NA | LECT2 Entrez, Source | leukocyte cell-derived chemotaxin 2 | 11095 | 0.128 | -0.0350 | No |
| 27 | FGG | NA | FGG Entrez, Source | fibrinogen gamma chain | 11357 | 0.115 | -0.0415 | No |
| 28 | C4BPA | NA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 11406 | 0.113 | -0.0402 | No |
| 29 | FGA | NA | FGA Entrez, Source | fibrinogen alpha chain | 11584 | 0.107 | -0.0438 | No |
| 30 | ASGR2 | NA | ASGR2 Entrez, Source | asialoglycoprotein receptor 2 | 11670 | 0.103 | -0.0441 | No |
| 31 | ITIH1 | NA | ITIH1 Entrez, Source | inter-alpha (globulin) inhibitor H1 | 11829 | 0.097 | -0.0473 | No |
| 32 | C9 | NA | C9 Entrez, Source | complement component 9 | 12675 | 0.065 | -0.0766 | No |
| 33 | AFM | NA | AFM Entrez, Source | afamin | 12795 | 0.061 | -0.0793 | No |
| 34 | APOB | NA | APOB Entrez, Source | apolipoprotein B (including Ag(x) antigen) | 13212 | 0.045 | -0.0934 | No |
| 35 | IGFBP1 | NA | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 13345 | 0.039 | -0.0971 | No |
| 36 | GC | NA | GC Entrez, Source | group-specific component (vitamin D binding protein) | 13564 | 0.030 | -0.1043 | No |
| 37 | ADH6 | NA | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 13644 | 0.028 | -0.1064 | No |
| 38 | CYP2C8 | NA | CYP2C8 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 8 | 14188 | 0.009 | -0.1261 | No |
| 39 | SAA4 | NA | SAA4 Entrez, Source | serum amyloid A4, constitutive | 14328 | 0.003 | -0.1311 | No |
| 40 | HRG | NA | HRG Entrez, Source | histidine-rich glycoprotein | 14436 | -0.000 | -0.1351 | No |
| 41 | F9 | NA | F9 Entrez, Source | coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) | 14642 | -0.008 | -0.1424 | No |
| 42 | FMO3 | NA | FMO3 Entrez, Source | flavin containing monooxygenase 3 | 14677 | -0.009 | -0.1434 | No |
| 43 | DPYS | NA | DPYS Entrez, Source | dihydropyrimidinase | 14745 | -0.011 | -0.1456 | No |
| 44 | CYP2C9 | NA | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 15109 | -0.026 | -0.1582 | No |
| 45 | CYP3A7 | NA | CYP3A7 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 7 | 15308 | -0.033 | -0.1645 | No |
| 46 | FGB | NA | FGB Entrez, Source | fibrinogen beta chain | 15433 | -0.038 | -0.1681 | No |
| 47 | SULT2A1 | NA | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 15584 | -0.044 | -0.1724 | No |
| 48 | C8A | NA | C8A Entrez, Source | complement component 8, alpha polypeptide | 15982 | -0.059 | -0.1854 | No |
| 49 | AMBP | NA | AMBP Entrez, Source | alpha-1-microglobulin/bikunin precursor | 15999 | -0.060 | -0.1843 | No |
| 50 | CFHR4 | NA | CFHR4 Entrez, Source | complement factor H-related 4 | 17272 | -0.113 | -0.2279 | No |
| 51 | ORM1 | NA | ORM1 Entrez, Source | orosomucoid 1 | 17369 | -0.118 | -0.2283 | No |
| 52 | SERPIND1 | NA | SERPIND1 Entrez, Source | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 17518 | -0.125 | -0.2303 | No |
| 53 | G6PC | NA | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 17848 | -0.144 | -0.2385 | No |
| 54 | FGL1 | NA | FGL1 Entrez, Source | fibrinogen-like 1 | 18242 | -0.168 | -0.2484 | No |
| 55 | TDO2 | NA | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 19263 | -0.249 | -0.2791 | No |
| 56 | F2 | NA | F2 Entrez, Source | coagulation factor II (thrombin) | 19293 | -0.251 | -0.2734 | No |
| 57 | C8B | NA | C8B Entrez, Source | complement component 8, beta polypeptide | 19296 | -0.251 | -0.2667 | No |
| 58 | HP | NA | HP Entrez, Source | haptoglobin | 19578 | -0.278 | -0.2695 | No |
| 59 | PLG | NA | PLG Entrez, Source | plasminogen | 19662 | -0.286 | -0.2648 | No |
| 60 | AKR1D1 | NA | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 20543 | -0.386 | -0.2866 | No |
| 61 | APOF | NA | APOF Entrez, Source | apolipoprotein F | 20849 | -0.430 | -0.2862 | No |
| 62 | ANG | NA | ANG Entrez, Source | angiogenin, ribonuclease, RNase A family, 5 | 21162 | -0.475 | -0.2848 | No |
| 63 | SERPINC1 | NA | SERPINC1 Entrez, Source | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 21754 | -0.582 | -0.2908 | No |
| 64 | HSD17B6 | NA | HSD17B6 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 6 | 22890 | -0.817 | -0.3103 | Yes |
| 65 | SLC22A1 | NA | SLC22A1 Entrez, Source | solute carrier family 22 (organic cation transporter), member 1 | 23357 | -0.916 | -0.3027 | Yes |
| 66 | C6 | NA | C6 Entrez, Source | complement component 6 | 24183 | -1.145 | -0.3020 | Yes |
| 67 | F12 | NA | F12 Entrez, Source | coagulation factor XII (Hageman factor) | 24354 | -1.196 | -0.2759 | Yes |
| 68 | AADAC | NA | AADAC Entrez, Source | arylacetamide deacetylase (esterase) | 25550 | -1.665 | -0.2748 | Yes |
| 69 | HRSP12 | NA | HRSP12 Entrez, Source | heat-responsive protein 12 | 25987 | -1.909 | -0.2392 | Yes |
| 70 | DHODH | NA | DHODH Entrez, Source | dihydroorotate dehydrogenase | 26441 | -2.251 | -0.1950 | Yes |
| 71 | CFH | NA | CFH Entrez, Source | complement factor H | 26651 | -2.446 | -0.1366 | Yes |
| 72 | APOC1 | NA | APOC1 Entrez, Source | apolipoprotein C-I | 26692 | -2.488 | -0.0708 | Yes |
| 73 | SLC27A2 | NA | SLC27A2 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 2 | 27135 | -3.486 | 0.0071 | Yes |
