Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_CD48 |
| Enrichment Score (ES) | -0.67846036 |
| Normalized Enrichment Score (NES) | -1.6257325 |
| Nominal p-value | 0.0038910506 |
| FDR q-value | 0.11348617 |
| FWER p-Value | 0.53 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CORO7 | NA | CORO7 Entrez, Source | coronin 7 | 832 | 2.447 | 0.0326 | No |
| 2 | LIMD2 | NA | LIMD2 Entrez, Source | LIM domain containing 2 | 4411 | 0.881 | -0.0758 | No |
| 3 | INPP5D | NA | INPP5D Entrez, Source | inositol polyphosphate-5-phosphatase, 145kDa | 5714 | 0.576 | -0.1086 | No |
| 4 | CORO1A | NA | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 9074 | 0.226 | -0.2258 | No |
| 5 | CSK | NA | CSK Entrez, Source | c-src tyrosine kinase | 12683 | 0.064 | -0.3563 | No |
| 6 | CD48 | NA | CD48 Entrez, Source | CD48 molecule | 13342 | 0.040 | -0.3794 | No |
| 7 | DOCK2 | NA | DOCK2 Entrez, Source | dedicator of cytokinesis 2 | 13996 | 0.015 | -0.4029 | No |
| 8 | PTPRC | NA | PTPRC Entrez, Source | protein tyrosine phosphatase, receptor type, C | 15992 | -0.059 | -0.4745 | No |
| 9 | PTPN6 | NA | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 16067 | -0.063 | -0.4756 | No |
| 10 | CD53 | NA | CD53 Entrez, Source | CD53 molecule | 16512 | -0.081 | -0.4898 | No |
| 11 | SASH3 | NA | 16842 | -0.095 | -0.4994 | No | ||
| 12 | TRIM38 | NA | TRIM38 Entrez, Source | tripartite motif-containing 38 | 17856 | -0.145 | -0.5328 | No |
| 13 | LAPTM5 | NA | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 18352 | -0.175 | -0.5464 | No |
| 14 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.5504 | No |
| 15 | HLA-A | NA | HLA-A Entrez, Source | major histocompatibility complex, class I, A | 19761 | -0.296 | -0.5853 | No |
| 16 | MBD2 | NA | MBD2 Entrez, Source | methyl-CpG binding domain protein 2 | 20839 | -0.428 | -0.6137 | No |
| 17 | RAC2 | NA | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 22044 | -0.636 | -0.6414 | No |
| 18 | GRK6 | NA | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 22437 | -0.715 | -0.6374 | No |
| 19 | HLA-F | NA | HLA-F Entrez, Source | major histocompatibility complex, class I, F | 23560 | -0.968 | -0.6535 | Yes |
| 20 | TAPBP | NA | TAPBP Entrez, Source | TAP binding protein (tapasin) | 23932 | -1.073 | -0.6394 | Yes |
| 21 | ARHGDIB | NA | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 24415 | -1.214 | -0.6258 | Yes |
| 22 | HLA-E | NA | HLA-E Entrez, Source | major histocompatibility complex, class I, E | 25321 | -1.557 | -0.6188 | Yes |
| 23 | TNFAIP8 | NA | TNFAIP8 Entrez, Source | tumor necrosis factor, alpha-induced protein 8 | 25842 | -1.819 | -0.5909 | Yes |
| 24 | SIPA1 | NA | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 26147 | -2.020 | -0.5500 | Yes |
| 25 | SP110 | NA | SP110 Entrez, Source | SP110 nuclear body protein | 26326 | -2.150 | -0.5011 | Yes |
| 26 | PSMB8 | NA | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 26617 | -2.405 | -0.4497 | Yes |
| 27 | PSMB10 | NA | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 26623 | -2.409 | -0.3877 | Yes |
| 28 | HLA-C | NA | HLA-C Entrez, Source | major histocompatibility complex, class I, C | 26647 | -2.442 | -0.3256 | Yes |
| 29 | HLA-B | NA | HLA-B Entrez, Source | major histocompatibility complex, class I, B | 26685 | -2.482 | -0.2630 | Yes |
| 30 | VAV1 | NA | VAV1 Entrez, Source | vav 1 oncogene | 27019 | -3.087 | -0.1956 | Yes |
| 31 | PHF11 | NA | PHF11 Entrez, Source | PHD finger protein 11 | 27141 | -3.511 | -0.1095 | Yes |
| 32 | STAT6 | NA | STAT6 Entrez, Source | signal transducer and activator of transcription 6, interleukin-4 induced | 27292 | -4.512 | 0.0014 | Yes |
