Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_HLA-C |
| Enrichment Score (ES) | -0.6427058 |
| Normalized Enrichment Score (NES) | -1.6421905 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.11895935 |
| FWER p-Value | 0.484 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CORO7 | NA | CORO7 Entrez, Source | coronin 7 | 832 | 2.447 | 0.0141 | No |
| 2 | KIAA0247 | NA | KIAA0247 Entrez, Source | KIAA0247 | 1484 | 1.986 | 0.0265 | No |
| 3 | MAX | NA | MAX Entrez, Source | MYC associated factor X | 4757 | 0.799 | -0.0789 | No |
| 4 | TRIM22 | NA | TRIM22 Entrez, Source | tripartite motif-containing 22 | 4914 | 0.763 | -0.0707 | No |
| 5 | C17orf62 | NA | C17ORF62 Entrez, Source | chromosome 17 open reading frame 62 | 5267 | 0.672 | -0.0714 | No |
| 6 | INPP5D | NA | INPP5D Entrez, Source | inositol polyphosphate-5-phosphatase, 145kDa | 5714 | 0.576 | -0.0772 | No |
| 7 | B2M | NA | B2M Entrez, Source | beta-2-microglobulin | 6491 | 0.454 | -0.0974 | No |
| 8 | PNRC1 | NA | PNRC1 Entrez, Source | proline-rich nuclear receptor coactivator 1 | 6677 | 0.431 | -0.0963 | No |
| 9 | CORO1A | NA | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 9074 | 0.226 | -0.1800 | No |
| 10 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 13022 | 0.052 | -0.3237 | No |
| 11 | ARF6 | NA | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 13142 | 0.047 | -0.3272 | No |
| 12 | CD48 | NA | CD48 Entrez, Source | CD48 molecule | 13342 | 0.040 | -0.3338 | No |
| 13 | PSD4 | NA | PSD4 Entrez, Source | pleckstrin and Sec7 domain containing 4 | 14922 | -0.018 | -0.3913 | No |
| 14 | GPSM3 | NA | GPSM3 Entrez, Source | G-protein signalling modulator 3 (AGS3-like, C. elegans) | 15135 | -0.027 | -0.3986 | No |
| 15 | TSC22D3 | NA | TSC22D3 Entrez, Source | TSC22 domain family, member 3 | 15412 | -0.037 | -0.4081 | No |
| 16 | PTPRC | NA | PTPRC Entrez, Source | protein tyrosine phosphatase, receptor type, C | 15992 | -0.059 | -0.4282 | No |
| 17 | PTPN6 | NA | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 16067 | -0.063 | -0.4298 | No |
| 18 | CD53 | NA | CD53 Entrez, Source | CD53 molecule | 16512 | -0.081 | -0.4446 | No |
| 19 | SASH3 | NA | 16842 | -0.095 | -0.4549 | No | ||
| 20 | LRCH4 | NA | LRCH4 Entrez, Source | leucine-rich repeats and calponin homology (CH) domain containing 4 | 16978 | -0.100 | -0.4580 | No |
| 21 | CYBA | NA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 17388 | -0.119 | -0.4708 | No |
| 22 | LAPTM5 | NA | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 18352 | -0.175 | -0.5029 | No |
| 23 | CYTIP | NA | 18503 | -0.186 | -0.5051 | No | ||
| 24 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.5050 | No |
| 25 | HLA-A | NA | HLA-A Entrez, Source | major histocompatibility complex, class I, A | 19761 | -0.296 | -0.5422 | No |
| 26 | RAC2 | NA | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 22044 | -0.636 | -0.6142 | No |
| 27 | GRK6 | NA | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 22437 | -0.715 | -0.6156 | No |
| 28 | SERP1 | NA | SERP1 Entrez, Source | - | 22652 | -0.765 | -0.6095 | No |
| 29 | HLA-F | NA | HLA-F Entrez, Source | major histocompatibility complex, class I, F | 23560 | -0.968 | -0.6251 | Yes |
| 30 | TAPBP | NA | TAPBP Entrez, Source | TAP binding protein (tapasin) | 23932 | -1.073 | -0.6191 | Yes |
| 31 | RIN3 | NA | RIN3 Entrez, Source | Ras and Rab interactor 3 | 23971 | -1.081 | -0.6008 | Yes |
| 32 | ARHGDIB | NA | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 24415 | -1.214 | -0.5949 | Yes |
| 33 | HLA-G | NA | HLA-G Entrez, Source | HLA-G histocompatibility antigen, class I, G | 24433 | -1.222 | -0.5732 | Yes |
| 34 | PRR13 | NA | PRR13 Entrez, Source | proline rich 13 | 24628 | -1.284 | -0.5569 | Yes |
| 35 | HLA-E | NA | HLA-E Entrez, Source | major histocompatibility complex, class I, E | 25321 | -1.557 | -0.5539 | Yes |
| 36 | TAP1 | NA | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 25740 | -1.759 | -0.5372 | Yes |
| 37 | IRF1 | NA | IRF1 Entrez, Source | interferon regulatory factor 1 | 25960 | -1.890 | -0.5107 | Yes |
| 38 | SIPA1 | NA | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 26147 | -2.020 | -0.4807 | Yes |
| 39 | PSMB10 | NA | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 26623 | -2.409 | -0.4542 | Yes |
| 40 | HLA-C | NA | HLA-C Entrez, Source | major histocompatibility complex, class I, C | 26647 | -2.442 | -0.4106 | Yes |
| 41 | HLA-B | NA | HLA-B Entrez, Source | major histocompatibility complex, class I, B | 26685 | -2.482 | -0.3667 | Yes |
| 42 | ELF4 | NA | ELF4 Entrez, Source | E74-like factor 4 (ets domain transcription factor) | 26906 | -2.819 | -0.3234 | Yes |
| 43 | VAV1 | NA | VAV1 Entrez, Source | vav 1 oncogene | 27019 | -3.087 | -0.2712 | Yes |
| 44 | PHF11 | NA | PHF11 Entrez, Source | PHD finger protein 11 | 27141 | -3.511 | -0.2116 | Yes |
| 45 | FXYD5 | NA | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 27160 | -3.575 | -0.1471 | Yes |
| 46 | HMHA1 | NA | HMHA1 Entrez, Source | histocompatibility (minor) HA-1 | 27216 | -3.895 | -0.0781 | Yes |
| 47 | STAT6 | NA | STAT6 Entrez, Source | signal transducer and activator of transcription 6, interleukin-4 induced | 27292 | -4.512 | 0.0014 | Yes |
