Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_ICAM3 |
| Enrichment Score (ES) | -0.5881797 |
| Normalized Enrichment Score (NES) | -1.6926879 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.08559327 |
| FWER p-Value | 0.339 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TXNIP | NA | TXNIP Entrez, Source | thioredoxin interacting protein | 806 | 2.466 | 0.0274 | No |
| 2 | TMEM127 | NA | TMEM127 Entrez, Source | transmembrane protein 127 | 2045 | 1.700 | 0.0212 | No |
| 3 | GIT2 | NA | GIT2 Entrez, Source | G protein-coupled receptor kinase interactor 2 | 2662 | 1.439 | 0.0318 | No |
| 4 | GMFG | NA | GMFG Entrez, Source | glia maturation factor, gamma | 4153 | 0.945 | -0.0010 | No |
| 5 | EMP3 | NA | EMP3 Entrez, Source | epithelial membrane protein 3 | 4602 | 0.842 | 0.0020 | No |
| 6 | MAX | NA | MAX Entrez, Source | MYC associated factor X | 4757 | 0.799 | 0.0148 | No |
| 7 | MYO1F | NA | MYO1F Entrez, Source | myosin IF | 6655 | 0.434 | -0.0447 | No |
| 8 | SLA | NA | SLA Entrez, Source | Src-like-adaptor | 7429 | 0.351 | -0.0649 | No |
| 9 | DAZAP2 | NA | DAZAP2 Entrez, Source | DAZ associated protein 2 | 8574 | 0.258 | -0.1009 | No |
| 10 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 13022 | 0.052 | -0.2626 | No |
| 11 | ACAP2 | NA | 13909 | 0.018 | -0.2947 | No | ||
| 12 | ARHGAP25 | NA | ARHGAP25 Entrez, Source | Rho GTPase activating protein 25 | 14307 | 0.004 | -0.3091 | No |
| 13 | ZCCHC6 | NA | ZCCHC6 Entrez, Source | zinc finger, CCHC domain containing 6 | 14810 | -0.013 | -0.3272 | No |
| 14 | GPSM3 | NA | GPSM3 Entrez, Source | G-protein signalling modulator 3 (AGS3-like, C. elegans) | 15135 | -0.027 | -0.3385 | No |
| 15 | DPEP2 | NA | DPEP2 Entrez, Source | dipeptidase 2 | 15503 | -0.041 | -0.3510 | No |
| 16 | PTPRC | NA | PTPRC Entrez, Source | protein tyrosine phosphatase, receptor type, C | 15992 | -0.059 | -0.3675 | No |
| 17 | PTPN6 | NA | PTPN6 Entrez, Source | protein tyrosine phosphatase, non-receptor type 6 | 16067 | -0.063 | -0.3687 | No |
| 18 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.4570 | No |
| 19 | LST1 | NA | LST1 Entrez, Source | leukocyte specific transcript 1 | 19299 | -0.251 | -0.4768 | No |
| 20 | PSTPIP1 | NA | PSTPIP1 Entrez, Source | proline-serine-threonine phosphatase interacting protein 1 | 19334 | -0.254 | -0.4722 | No |
| 21 | SH3BGRL3 | NA | SH3BGRL3 Entrez, Source | SH3 domain binding glutamic acid-rich protein like 3 | 19779 | -0.297 | -0.4816 | No |
| 22 | ADAM8 | NA | ADAM8 Entrez, Source | ADAM metallopeptidase domain 8 | 20906 | -0.438 | -0.5128 | No |
| 23 | SELL | NA | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 21687 | -0.568 | -0.5283 | No |
| 24 | ARRB2 | NA | ARRB2 Entrez, Source | arrestin, beta 2 | 23323 | -0.906 | -0.5673 | Yes |
| 25 | HLA-F | NA | HLA-F Entrez, Source | major histocompatibility complex, class I, F | 23560 | -0.968 | -0.5536 | Yes |
| 26 | FAM65B | NA | 23650 | -0.993 | -0.5340 | Yes | ||
| 27 | GMIP | NA | GMIP Entrez, Source | GEM interacting protein | 23688 | -1.003 | -0.5122 | Yes |
| 28 | RIN3 | NA | RIN3 Entrez, Source | Ras and Rab interactor 3 | 23971 | -1.081 | -0.4976 | Yes |
| 29 | HLA-G | NA | HLA-G Entrez, Source | HLA-G histocompatibility antigen, class I, G | 24433 | -1.222 | -0.4863 | Yes |
| 30 | ITGB2 | NA | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 24721 | -1.317 | -0.4664 | Yes |
| 31 | HSD17B11 | NA | 25014 | -1.423 | -0.4443 | Yes | ||
| 32 | HLA-E | NA | HLA-E Entrez, Source | major histocompatibility complex, class I, E | 25321 | -1.557 | -0.4196 | Yes |
| 33 | IRF1 | NA | IRF1 Entrez, Source | interferon regulatory factor 1 | 25960 | -1.890 | -0.3994 | Yes |
| 34 | EVI2B | NA | EVI2B Entrez, Source | ecotropic viral integration site 2B | 27063 | -3.219 | -0.3655 | Yes |
| 35 | FMNL1 | NA | FMNL1 Entrez, Source | formin-like 1 | 27118 | -3.438 | -0.2882 | Yes |
| 36 | CASP4 | NA | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 27208 | -3.856 | -0.2025 | Yes |
| 37 | ICAM3 | NA | ICAM3 Entrez, Source | intercellular adhesion molecule 3 | 27285 | -4.456 | -0.1025 | Yes |
| 38 | STAT6 | NA | STAT6 Entrez, Source | signal transducer and activator of transcription 6, interleukin-4 induced | 27292 | -4.512 | 0.0014 | Yes |
