Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_INPP5D |
| Enrichment Score (ES) | -0.65197504 |
| Normalized Enrichment Score (NES) | -1.8331305 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.04043524 |
| FWER p-Value | 0.083 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ACTR3 | NA | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 2933 | 1.337 | -0.0800 | No |
| 2 | RAP1B | NA | RAP1B Entrez, Source | RAP1B, member of RAS oncogene family | 3608 | 1.113 | -0.0818 | No |
| 3 | CSNK1G2 | NA | CSNK1G2 Entrez, Source | casein kinase 1, gamma 2 | 4166 | 0.941 | -0.0829 | No |
| 4 | MFNG | NA | MFNG Entrez, Source | manic fringe homolog (Drosophila) | 4627 | 0.832 | -0.0826 | No |
| 5 | C17orf62 | NA | C17ORF62 Entrez, Source | chromosome 17 open reading frame 62 | 5267 | 0.672 | -0.0922 | No |
| 6 | RNF4 | NA | RNF4 Entrez, Source | ring finger protein 4 | 5509 | 0.616 | -0.0884 | No |
| 7 | INPP5D | NA | INPP5D Entrez, Source | inositol polyphosphate-5-phosphatase, 145kDa | 5714 | 0.576 | -0.0840 | No |
| 8 | WIPF1 | NA | WIPF1 Entrez, Source | WAS/WASL interacting protein family, member 1 | 5979 | 0.531 | -0.0828 | No |
| 9 | STK10 | NA | STK10 Entrez, Source | serine/threonine kinase 10 | 6014 | 0.524 | -0.0732 | No |
| 10 | CORO1A | NA | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 9074 | 0.226 | -0.1807 | No |
| 11 | CSK | NA | CSK Entrez, Source | c-src tyrosine kinase | 12683 | 0.064 | -0.3116 | No |
| 12 | CBFB | NA | CBFB Entrez, Source | core-binding factor, beta subunit | 12748 | 0.062 | -0.3127 | No |
| 13 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 13022 | 0.052 | -0.3216 | No |
| 14 | ARF6 | NA | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 13142 | 0.047 | -0.3250 | No |
| 15 | CD48 | NA | CD48 Entrez, Source | CD48 molecule | 13342 | 0.040 | -0.3315 | No |
| 16 | PSD4 | NA | PSD4 Entrez, Source | pleckstrin and Sec7 domain containing 4 | 14922 | -0.018 | -0.3890 | No |
| 17 | CD53 | NA | CD53 Entrez, Source | CD53 molecule | 16512 | -0.081 | -0.4455 | No |
| 18 | SASH3 | NA | 16842 | -0.095 | -0.4556 | No | ||
| 19 | LAPTM5 | NA | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 18352 | -0.175 | -0.5073 | No |
| 20 | CYTIP | NA | 18503 | -0.186 | -0.5090 | No | ||
| 21 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.5085 | No |
| 22 | KDM5A | NA | 18793 | -0.209 | -0.5113 | No | ||
| 23 | HLA-A | NA | HLA-A Entrez, Source | major histocompatibility complex, class I, A | 19761 | -0.296 | -0.5406 | No |
| 24 | RAC2 | NA | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 22044 | -0.636 | -0.6112 | No |
| 25 | GRK6 | NA | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 22437 | -0.715 | -0.6109 | No |
| 26 | HLA-F | NA | HLA-F Entrez, Source | major histocompatibility complex, class I, F | 23560 | -0.968 | -0.6321 | Yes |
| 27 | TAPBP | NA | TAPBP Entrez, Source | TAP binding protein (tapasin) | 23932 | -1.073 | -0.6236 | Yes |
| 28 | PSME1 | NA | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 23933 | -1.073 | -0.6015 | Yes |
| 29 | ARHGDIB | NA | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 24415 | -1.214 | -0.5942 | Yes |
| 30 | HLA-G | NA | HLA-G Entrez, Source | HLA-G histocompatibility antigen, class I, G | 24433 | -1.222 | -0.5697 | Yes |
| 31 | CDV3 | NA | CDV3 Entrez, Source | CDV3 homolog (mouse) | 25320 | -1.557 | -0.5701 | Yes |
| 32 | HLA-E | NA | HLA-E Entrez, Source | major histocompatibility complex, class I, E | 25321 | -1.557 | -0.5381 | Yes |
| 33 | TAP1 | NA | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 25740 | -1.759 | -0.5172 | Yes |
| 34 | SIPA1 | NA | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 26147 | -2.020 | -0.4906 | Yes |
| 35 | IFI16 | NA | IFI16 Entrez, Source | interferon, gamma-inducible protein 16 | 26475 | -2.276 | -0.4558 | Yes |
| 36 | PSMB8 | NA | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 26617 | -2.405 | -0.4115 | Yes |
| 37 | PSMB10 | NA | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 26623 | -2.409 | -0.3621 | Yes |
| 38 | HLA-C | NA | HLA-C Entrez, Source | major histocompatibility complex, class I, C | 26647 | -2.442 | -0.3127 | Yes |
| 39 | HLA-B | NA | HLA-B Entrez, Source | major histocompatibility complex, class I, B | 26685 | -2.482 | -0.2630 | Yes |
| 40 | ELF4 | NA | ELF4 Entrez, Source | E74-like factor 4 (ets domain transcription factor) | 26906 | -2.819 | -0.2131 | Yes |
| 41 | VAV1 | NA | VAV1 Entrez, Source | vav 1 oncogene | 27019 | -3.087 | -0.1537 | Yes |
| 42 | PHF11 | NA | PHF11 Entrez, Source | PHD finger protein 11 | 27141 | -3.511 | -0.0859 | Yes |
| 43 | STAT6 | NA | STAT6 Entrez, Source | signal transducer and activator of transcription 6, interleukin-4 induced | 27292 | -4.512 | 0.0014 | Yes |
