Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_ITGB2 |
| Enrichment Score (ES) | -0.5267821 |
| Normalized Enrichment Score (NES) | -1.6418641 |
| Nominal p-value | 0.0019646366 |
| FDR q-value | 0.11156643 |
| FWER p-Value | 0.484 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CD97 | NA | CD97 Entrez, Source | CD97 molecule | 187 | 3.291 | 0.0477 | No |
| 2 | RGS2 | NA | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 561 | 2.704 | 0.0788 | No |
| 3 | TMEM127 | NA | TMEM127 Entrez, Source | transmembrane protein 127 | 2045 | 1.700 | 0.0526 | No |
| 4 | C1orf38 | NA | C1ORF38 Entrez, Source | chromosome 1 open reading frame 38 | 3097 | 1.278 | 0.0353 | No |
| 5 | FBXL5 | NA | FBXL5 Entrez, Source | F-box and leucine-rich repeat protein 5 | 3322 | 1.208 | 0.0471 | No |
| 6 | PLCB2 | NA | PLCB2 Entrez, Source | phospholipase C, beta 2 | 4037 | 0.977 | 0.0371 | No |
| 7 | GMFG | NA | GMFG Entrez, Source | glia maturation factor, gamma | 4153 | 0.945 | 0.0485 | No |
| 8 | LILRA1 | NA | LILRA1 Entrez, Source | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 5339 | 0.652 | 0.0159 | No |
| 9 | S100A4 | NA | S100A4 Entrez, Source | S100 calcium binding protein A4 | 6035 | 0.521 | -0.0010 | No |
| 10 | BIN2 | NA | BIN2 Entrez, Source | bridging integrator 2 | 6398 | 0.466 | -0.0065 | No |
| 11 | MYO1F | NA | MYO1F Entrez, Source | myosin IF | 6655 | 0.434 | -0.0087 | No |
| 12 | TNFRSF1B | NA | TNFRSF1B Entrez, Source | tumor necrosis factor receptor superfamily, member 1B | 7512 | 0.343 | -0.0344 | No |
| 13 | PECAM1 | NA | PECAM1 Entrez, Source | platelet/endothelial cell adhesion molecule (CD31 antigen) | 10099 | 0.174 | -0.1263 | No |
| 14 | TYROBP | NA | TYROBP Entrez, Source | TYRO protein tyrosine kinase binding protein | 10577 | 0.152 | -0.1413 | No |
| 15 | CMTM6 | NA | CMTM6 Entrez, Source | CKLF-like MARVEL transmembrane domain containing 6 | 10920 | 0.136 | -0.1516 | No |
| 16 | MSN | NA | MSN Entrez, Source | moesin | 11240 | 0.121 | -0.1613 | No |
| 17 | CECR1 | NA | CECR1 Entrez, Source | cat eye syndrome chromosome region, candidate 1 | 11840 | 0.096 | -0.1816 | No |
| 18 | DOK2 | NA | DOK2 Entrez, Source | docking protein 2, 56kDa | 11962 | 0.092 | -0.1845 | No |
| 19 | PYCARD | NA | PYCARD Entrez, Source | PYD and CARD domain containing | 12017 | 0.090 | -0.1850 | No |
| 20 | IL10RA | NA | IL10RA Entrez, Source | interleukin 10 receptor, alpha | 12399 | 0.075 | -0.1978 | No |
| 21 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 13022 | 0.052 | -0.2197 | No |
| 22 | HCK | NA | HCK Entrez, Source | hemopoietic cell kinase | 13795 | 0.023 | -0.2476 | No |
| 23 | ACAP2 | NA | 13909 | 0.018 | -0.2515 | No | ||
| 24 | FCER1G | NA | FCER1G Entrez, Source | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 14128 | 0.011 | -0.2593 | No |
| 25 | SELPLG | NA | SELPLG Entrez, Source | selectin P ligand | 14342 | 0.003 | -0.2671 | No |
| 26 | AIF1 | NA | AIF1 Entrez, Source | allograft inflammatory factor 1 | 14416 | 0.001 | -0.2697 | No |
| 27 | ZCCHC6 | NA | ZCCHC6 Entrez, Source | zinc finger, CCHC domain containing 6 | 14810 | -0.013 | -0.2839 | No |
| 28 | DPEP2 | NA | DPEP2 Entrez, Source | dipeptidase 2 | 15503 | -0.041 | -0.3086 | No |
| 29 | AOAH | NA | AOAH Entrez, Source | acyloxyacyl hydrolase (neutrophil) | 16347 | -0.075 | -0.3383 | No |
| 30 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.4176 | No |
| 31 | ITGAX | NA | ITGAX Entrez, Source | integrin, alpha X (complement component 3 receptor 4 subunit) | 18791 | -0.209 | -0.4211 | No |
| 32 | LST1 | NA | LST1 Entrez, Source | leukocyte specific transcript 1 | 19299 | -0.251 | -0.4356 | No |
| 33 | PSTPIP1 | NA | PSTPIP1 Entrez, Source | proline-serine-threonine phosphatase interacting protein 1 | 19334 | -0.254 | -0.4326 | No |
| 34 | SH3BGRL3 | NA | SH3BGRL3 Entrez, Source | SH3 domain binding glutamic acid-rich protein like 3 | 19779 | -0.297 | -0.4440 | No |
| 35 | FGR | NA | FGR Entrez, Source | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 20557 | -0.387 | -0.4660 | No |
| 36 | ADAM8 | NA | ADAM8 Entrez, Source | ADAM metallopeptidase domain 8 | 20906 | -0.438 | -0.4715 | No |
| 37 | RHOG | NA | RHOG Entrez, Source | ras homolog gene family, member G (rho G) | 22134 | -0.653 | -0.5057 | No |
| 38 | ITGAM | NA | ITGAM Entrez, Source | integrin, alpha M (complement component 3 receptor 3 subunit) | 22152 | -0.657 | -0.4954 | No |
| 39 | IQGAP1 | NA | IQGAP1 Entrez, Source | IQ motif containing GTPase activating protein 1 | 22330 | -0.693 | -0.4904 | No |
| 40 | ARRB2 | NA | ARRB2 Entrez, Source | arrestin, beta 2 | 23323 | -0.906 | -0.5118 | Yes |
| 41 | GMIP | NA | GMIP Entrez, Source | GEM interacting protein | 23688 | -1.003 | -0.5085 | Yes |
| 42 | MCL1 | NA | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 23722 | -1.013 | -0.4929 | Yes |
| 43 | RIN3 | NA | RIN3 Entrez, Source | Ras and Rab interactor 3 | 23971 | -1.081 | -0.4841 | Yes |
| 44 | EFHD2 | NA | EFHD2 Entrez, Source | EF-hand domain family, member D2 | 24126 | -1.127 | -0.4710 | Yes |
| 45 | ITGB2 | NA | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 24721 | -1.317 | -0.4710 | Yes |
| 46 | HSD17B11 | NA | 25014 | -1.423 | -0.4581 | Yes | ||
| 47 | IRF1 | NA | IRF1 Entrez, Source | interferon regulatory factor 1 | 25960 | -1.890 | -0.4614 | Yes |
| 48 | RAB27A | NA | RAB27A Entrez, Source | RAB27A, member RAS oncogene family | 26660 | -2.456 | -0.4463 | Yes |
| 49 | TCIRG1 | NA | TCIRG1 Entrez, Source | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 26835 | -2.712 | -0.4078 | Yes |
| 50 | ELF4 | NA | ELF4 Entrez, Source | E74-like factor 4 (ets domain transcription factor) | 26906 | -2.819 | -0.3636 | Yes |
| 51 | CASP1 | NA | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 26974 | -2.959 | -0.3170 | Yes |
| 52 | FMNL1 | NA | FMNL1 Entrez, Source | formin-like 1 | 27118 | -3.438 | -0.2653 | Yes |
| 53 | MYD88 | NA | MYD88 Entrez, Source | myeloid differentiation primary response gene (88) | 27181 | -3.688 | -0.2064 | Yes |
| 54 | PTGER4 | NA | PTGER4 Entrez, Source | prostaglandin E receptor 4 (subtype EP4) | 27226 | -3.974 | -0.1422 | Yes |
| 55 | OSTF1 | NA | OSTF1 Entrez, Source | osteoclast stimulating factor 1 | 27276 | -4.343 | -0.0720 | Yes |
| 56 | ICAM3 | NA | ICAM3 Entrez, Source | intercellular adhesion molecule 3 | 27285 | -4.456 | 0.0016 | Yes |
