Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | GNF2_MAPT |
| Enrichment Score (ES) | 0.6934298 |
| Normalized Enrichment Score (NES) | 1.6979692 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07137757 |
| FWER p-Value | 0.345 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PNMA2 | NA | PNMA2 Entrez, Source | paraneoplastic antigen MA2 | 36 | 3.757 | 0.0591 | Yes |
| 2 | MAPT | NA | MAPT Entrez, Source | microtubule-associated protein tau | 96 | 3.498 | 0.1133 | Yes |
| 3 | BAI3 | NA | BAI3 Entrez, Source | brain-specific angiogenesis inhibitor 3 | 154 | 3.346 | 0.1650 | Yes |
| 4 | GPM6A | NA | GPM6A Entrez, Source | glycoprotein M6A | 168 | 3.322 | 0.2180 | Yes |
| 5 | PSD3 | NA | PSD3 Entrez, Source | pleckstrin and Sec7 domain containing 3 | 247 | 3.182 | 0.2664 | Yes |
| 6 | CLIP3 | NA | 421 | 2.902 | 0.3067 | Yes | ||
| 7 | ARNT2 | NA | ARNT2 Entrez, Source | aryl-hydrocarbon receptor nuclear translocator 2 | 541 | 2.730 | 0.3463 | Yes |
| 8 | ELAVL4 | NA | ELAVL4 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) | 674 | 2.596 | 0.3833 | Yes |
| 9 | SV2A | NA | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 713 | 2.560 | 0.4231 | Yes |
| 10 | CAMK2N1 | NA | CAMK2N1 Entrez, Source | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 1064 | 2.270 | 0.4468 | Yes |
| 11 | RTN1 | NA | RTN1 Entrez, Source | reticulon 1 | 1084 | 2.254 | 0.4824 | Yes |
| 12 | KIF5C | NA | KIF5C Entrez, Source | kinesin family member 5C | 1092 | 2.248 | 0.5183 | Yes |
| 13 | GRIA2 | NA | GRIA2 Entrez, Source | glutamate receptor, ionotropic, AMPA 2 | 1575 | 1.936 | 0.5318 | Yes |
| 14 | SLC1A3 | NA | SLC1A3 Entrez, Source | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 1607 | 1.921 | 0.5616 | Yes |
| 15 | GABBR2 | NA | GABBR2 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 2 | 1803 | 1.821 | 0.5837 | Yes |
| 16 | ANK2 | NA | ANK2 Entrez, Source | ankyrin 2, neuronal | 2346 | 1.577 | 0.5893 | Yes |
| 17 | RAB6B | NA | RAB6B Entrez, Source | RAB6B, member RAS oncogene family | 2459 | 1.524 | 0.6097 | Yes |
| 18 | DNM1 | NA | DNM1 Entrez, Source | dynamin 1 | 2462 | 1.521 | 0.6341 | Yes |
| 19 | GAP43 | NA | GAP43 Entrez, Source | growth associated protein 43 | 2743 | 1.403 | 0.6464 | Yes |
| 20 | KIF1B | NA | KIF1B Entrez, Source | kinesin family member 1B | 2755 | 1.397 | 0.6685 | Yes |
| 21 | KCNQ2 | NA | KCNQ2 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 2 | 3310 | 1.211 | 0.6677 | Yes |
| 22 | PALM | NA | PALM Entrez, Source | paralemmin | 3528 | 1.145 | 0.6782 | Yes |
| 23 | DYNC1I1 | NA | DYNC1I1 Entrez, Source | dynein, cytoplasmic 1, intermediate chain 1 | 3602 | 1.115 | 0.6934 | Yes |
| 24 | RUNDC3A | NA | 7643 | 0.331 | 0.5507 | No | ||
| 25 | SH3GL2 | NA | SH3GL2 Entrez, Source | SH3-domain GRB2-like 2 | 8223 | 0.283 | 0.5341 | No |
| 26 | SCN3B | NA | SCN3B Entrez, Source | sodium channel, voltage-gated, type III, beta | 9054 | 0.226 | 0.5073 | No |
| 27 | NRXN1 | NA | NRXN1 Entrez, Source | neurexin 1 | 10464 | 0.158 | 0.4582 | No |
| 28 | DOCK3 | NA | DOCK3 Entrez, Source | dedicator of cytokinesis 3 | 12347 | 0.077 | 0.3905 | No |
| 29 | SYN1 | NA | SYN1 Entrez, Source | synapsin I | 13172 | 0.046 | 0.3610 | No |
| 30 | DIRAS2 | NA | DIRAS2 Entrez, Source | DIRAS family, GTP-binding RAS-like 2 | 15437 | -0.038 | 0.2787 | No |
| 31 | SV2B | NA | SV2B Entrez, Source | synaptic vesicle glycoprotein 2B | 17293 | -0.115 | 0.2125 | No |
| 32 | RALYL | NA | 17456 | -0.122 | 0.2086 | No | ||
| 33 | RGS7 | NA | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 17631 | -0.130 | 0.2043 | No |
| 34 | SNCB | NA | SNCB Entrez, Source | synuclein, beta | 19574 | -0.278 | 0.1376 | No |
| 35 | FXYD7 | NA | FXYD7 Entrez, Source | FXYD domain containing ion transport regulator 7 | 20263 | -0.350 | 0.1180 | No |
| 36 | NPTXR | NA | NPTXR Entrez, Source | neuronal pentraxin receptor | 20743 | -0.414 | 0.1071 | No |
| 37 | GNAO1 | NA | GNAO1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 23419 | -0.930 | 0.0241 | No |
| 38 | SNAP91 | NA | SNAP91 Entrez, Source | synaptosomal-associated protein, 91kDa homolog (mouse) | 24696 | -1.307 | -0.0017 | No |
| 39 | STXBP1 | NA | STXBP1 Entrez, Source | syntaxin binding protein 1 | 25687 | -1.735 | -0.0100 | No |
| 40 | SYT1 | NA | SYT1 Entrez, Source | synaptotagmin I | 26109 | -1.987 | 0.0065 | No |
| 41 | NAP1L3 | NA | NAP1L3 Entrez, Source | nucleosome assembly protein 1-like 3 | 26583 | -2.369 | 0.0273 | No |
