Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_PAK2 |
| Enrichment Score (ES) | -0.6086099 |
| Normalized Enrichment Score (NES) | -1.9482526 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.02203542 |
| FWER p-Value | 0.02 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PHF21A | NA | PHF21A Entrez, Source | PHD finger protein 21A | 1688 | 1.878 | 0.0050 | No |
| 2 | ACTR3 | NA | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 2933 | 1.337 | 0.0070 | No |
| 3 | GMFG | NA | GMFG Entrez, Source | glia maturation factor, gamma | 4153 | 0.945 | -0.0041 | No |
| 4 | RAF1 | NA | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 4307 | 0.905 | 0.0225 | No |
| 5 | BNIP2 | NA | BNIP2 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 2 | 7308 | 0.365 | -0.0744 | No |
| 6 | OSBPL8 | NA | OSBPL8 Entrez, Source | oxysterol binding protein-like 8 | 8418 | 0.269 | -0.1055 | No |
| 7 | ARPC3 | NA | ARPC3 Entrez, Source | actin related protein 2/3 complex, subunit 3, 21kDa | 8966 | 0.232 | -0.1173 | No |
| 8 | TYK2 | NA | TYK2 Entrez, Source | tyrosine kinase 2 | 9609 | 0.197 | -0.1338 | No |
| 9 | CNOT8 | NA | CNOT8 Entrez, Source | CCR4-NOT transcription complex, subunit 8 | 10156 | 0.172 | -0.1477 | No |
| 10 | PAK2 | NA | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 11208 | 0.122 | -0.1818 | No |
| 11 | ADAM10 | NA | ADAM10 Entrez, Source | ADAM metallopeptidase domain 10 | 11952 | 0.092 | -0.2057 | No |
| 12 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 13022 | 0.052 | -0.2431 | No |
| 13 | ACAP2 | NA | 13909 | 0.018 | -0.2749 | No | ||
| 14 | DOCK2 | NA | DOCK2 Entrez, Source | dedicator of cytokinesis 2 | 13996 | 0.015 | -0.2775 | No |
| 15 | ZCCHC6 | NA | ZCCHC6 Entrez, Source | zinc finger, CCHC domain containing 6 | 14810 | -0.013 | -0.3068 | No |
| 16 | CD53 | NA | CD53 Entrez, Source | CD53 molecule | 16512 | -0.081 | -0.3662 | No |
| 17 | ACTR2 | NA | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 18307 | -0.173 | -0.4257 | No |
| 18 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.4295 | No |
| 19 | ARPC5 | NA | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 20291 | -0.354 | -0.4789 | No |
| 20 | CAPZA1 | NA | CAPZA1 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 1 | 21240 | -0.487 | -0.4963 | No |
| 21 | SELL | NA | SELL Entrez, Source | selectin L (lymphocyte adhesion molecule 1) | 21687 | -0.568 | -0.4924 | No |
| 22 | USP3 | NA | USP3 Entrez, Source | ubiquitin specific peptidase 3 | 23247 | -0.891 | -0.5179 | Yes |
| 23 | ARHGDIB | NA | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 24415 | -1.214 | -0.5174 | Yes |
| 24 | ELF4 | NA | ELF4 Entrez, Source | E74-like factor 4 (ets domain transcription factor) | 26906 | -2.819 | -0.5084 | Yes |
| 25 | VAV1 | NA | VAV1 Entrez, Source | vav 1 oncogene | 27019 | -3.087 | -0.4027 | Yes |
| 26 | FMNL1 | NA | FMNL1 Entrez, Source | formin-like 1 | 27118 | -3.438 | -0.2840 | Yes |
| 27 | MYD88 | NA | MYD88 Entrez, Source | myeloid differentiation primary response gene (88) | 27181 | -3.688 | -0.1551 | Yes |
| 28 | STAT6 | NA | STAT6 Entrez, Source | signal transducer and activator of transcription 6, interleukin-4 induced | 27292 | -4.512 | 0.0014 | Yes |
