Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | GNF2_VAV1 |
| Enrichment Score (ES) | -0.6752205 |
| Normalized Enrichment Score (NES) | -1.69814 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.08760703 |
| FWER p-Value | 0.324 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CORO7 | NA | CORO7 Entrez, Source | coronin 7 | 832 | 2.447 | 0.0269 | No |
| 2 | GIT2 | NA | GIT2 Entrez, Source | G protein-coupled receptor kinase interactor 2 | 2662 | 1.439 | -0.0064 | No |
| 3 | TRIM22 | NA | TRIM22 Entrez, Source | tripartite motif-containing 22 | 4914 | 0.763 | -0.0709 | No |
| 4 | INPP5D | NA | INPP5D Entrez, Source | inositol polyphosphate-5-phosphatase, 145kDa | 5714 | 0.576 | -0.0867 | No |
| 5 | CORO1A | NA | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 9074 | 0.226 | -0.2045 | No |
| 6 | PAK2 | NA | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 11208 | 0.122 | -0.2798 | No |
| 7 | CSK | NA | CSK Entrez, Source | c-src tyrosine kinase | 12683 | 0.064 | -0.3323 | No |
| 8 | WAS | NA | WAS Entrez, Source | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 13022 | 0.052 | -0.3434 | No |
| 9 | CD48 | NA | CD48 Entrez, Source | CD48 molecule | 13342 | 0.040 | -0.3542 | No |
| 10 | DOCK2 | NA | DOCK2 Entrez, Source | dedicator of cytokinesis 2 | 13996 | 0.015 | -0.3777 | No |
| 11 | GPSM3 | NA | GPSM3 Entrez, Source | G-protein signalling modulator 3 (AGS3-like, C. elegans) | 15135 | -0.027 | -0.4188 | No |
| 12 | PTPRC | NA | PTPRC Entrez, Source | protein tyrosine phosphatase, receptor type, C | 15992 | -0.059 | -0.4488 | No |
| 13 | CD53 | NA | CD53 Entrez, Source | CD53 molecule | 16512 | -0.081 | -0.4659 | No |
| 14 | SASH3 | NA | 16842 | -0.095 | -0.4757 | No | ||
| 15 | CYBA | NA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 17388 | -0.119 | -0.4929 | No |
| 16 | TRIM38 | NA | TRIM38 Entrez, Source | tripartite motif-containing 38 | 17856 | -0.145 | -0.5066 | No |
| 17 | ACTR2 | NA | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 18307 | -0.173 | -0.5191 | No |
| 18 | LAPTM5 | NA | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 18352 | -0.175 | -0.5166 | No |
| 19 | CYTIP | NA | 18503 | -0.186 | -0.5177 | No | ||
| 20 | HCLS1 | NA | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 18598 | -0.193 | -0.5166 | No |
| 21 | RAC2 | NA | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 22044 | -0.636 | -0.6279 | No |
| 22 | GRK6 | NA | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 22437 | -0.715 | -0.6255 | No |
| 23 | HLA-F | NA | HLA-F Entrez, Source | major histocompatibility complex, class I, F | 23560 | -0.968 | -0.6439 | No |
| 24 | ARHGDIB | NA | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 24415 | -1.214 | -0.6467 | Yes |
| 25 | HLA-G | NA | HLA-G Entrez, Source | HLA-G histocompatibility antigen, class I, G | 24433 | -1.222 | -0.6187 | Yes |
| 26 | HLA-E | NA | HLA-E Entrez, Source | major histocompatibility complex, class I, E | 25321 | -1.557 | -0.6147 | Yes |
| 27 | PIK3CD | NA | PIK3CD Entrez, Source | phosphoinositide-3-kinase, catalytic, delta polypeptide | 25366 | -1.579 | -0.5793 | Yes |
| 28 | SP110 | NA | SP110 Entrez, Source | SP110 nuclear body protein | 26326 | -2.150 | -0.5640 | Yes |
| 29 | PSMB10 | NA | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 26623 | -2.409 | -0.5183 | Yes |
| 30 | HLA-C | NA | HLA-C Entrez, Source | major histocompatibility complex, class I, C | 26647 | -2.442 | -0.4619 | Yes |
| 31 | HLA-B | NA | HLA-B Entrez, Source | major histocompatibility complex, class I, B | 26685 | -2.482 | -0.4051 | Yes |
| 32 | ELF4 | NA | ELF4 Entrez, Source | E74-like factor 4 (ets domain transcription factor) | 26906 | -2.819 | -0.3470 | Yes |
| 33 | VAV1 | NA | VAV1 Entrez, Source | vav 1 oncogene | 27019 | -3.087 | -0.2787 | Yes |
| 34 | PHF11 | NA | PHF11 Entrez, Source | PHD finger protein 11 | 27141 | -3.511 | -0.2008 | Yes |
| 35 | OSTF1 | NA | OSTF1 Entrez, Source | osteoclast stimulating factor 1 | 27276 | -4.343 | -0.1039 | Yes |
| 36 | STAT6 | NA | STAT6 Entrez, Source | signal transducer and activator of transcription 6, interleukin-4 induced | 27292 | -4.512 | 0.0014 | Yes |
