Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | MODULE_134 |
| Enrichment Score (ES) | 0.4800689 |
| Normalized Enrichment Score (NES) | 1.943728 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.009946386 |
| FWER p-Value | 0.024 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CXCR4 | NA | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 51 | 3.653 | 0.1973 | Yes |
| 2 | C3AR1 | NA | C3AR1 Entrez, Source | complement component 3a receptor 1 | 718 | 2.553 | 0.3121 | Yes |
| 3 | EDNRB | NA | EDNRB Entrez, Source | endothelin receptor type B | 1044 | 2.286 | 0.4249 | Yes |
| 4 | CCR1 | NA | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 2059 | 1.692 | 0.4801 | Yes |
| 5 | GALR3 | NA | GALR3 Entrez, Source | galanin receptor 3 | 7800 | 0.318 | 0.2871 | No |
| 6 | CXCR5 | NA | 8601 | 0.256 | 0.2718 | No | ||
| 7 | FPR1 | NA | FPR1 Entrez, Source | formyl peptide receptor 1 | 9604 | 0.197 | 0.2459 | No |
| 8 | NPY5R | NA | NPY5R Entrez, Source | neuropeptide Y receptor Y5 | 10484 | 0.156 | 0.2222 | No |
| 9 | CCBP2 | NA | CCBP2 Entrez, Source | chemokine binding protein 2 | 11068 | 0.129 | 0.2079 | No |
| 10 | MAS1 | NA | MAS1 Entrez, Source | MAS1 oncogene | 11464 | 0.112 | 0.1995 | No |
| 11 | HCRTR1 | NA | HCRTR1 Entrez, Source | hypocretin (orexin) receptor 1 | 12423 | 0.074 | 0.1684 | No |
| 12 | CCR4 | NA | CCR4 Entrez, Source | chemokine (C-C motif) receptor 4 | 12958 | 0.054 | 0.1518 | No |
| 13 | CCR5 | NA | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 13865 | 0.020 | 0.1197 | No |
| 14 | OPRK1 | NA | OPRK1 Entrez, Source | opioid receptor, kappa 1 | 14020 | 0.014 | 0.1149 | No |
| 15 | CX3CR1 | NA | CX3CR1 Entrez, Source | chemokine (C-X3-C motif) receptor 1 | 14724 | -0.011 | 0.0897 | No |
| 16 | GPR17 | NA | GPR17 Entrez, Source | G protein-coupled receptor 17 | 15321 | -0.034 | 0.0697 | No |
| 17 | AVPR1A | NA | AVPR1A Entrez, Source | arginine vasopressin receptor 1A | 15785 | -0.051 | 0.0556 | No |
| 18 | CXCR6 | NA | CXCR6 Entrez, Source | chemokine (C-X-C motif) receptor 6 | 16380 | -0.076 | 0.0380 | No |
| 19 | CCR2 | NA | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 16547 | -0.083 | 0.0364 | No |
| 20 | CCKAR | NA | CCKAR Entrez, Source | cholecystokinin A receptor | 16682 | -0.088 | 0.0363 | No |
| 21 | FPR2 | NA | 17173 | -0.109 | 0.0243 | No | ||
| 22 | C5AR1 | NA | C5AR1 Entrez, Source | complement component 5a receptor 1 | 17675 | -0.133 | 0.0132 | No |
| 23 | EDNRA | NA | EDNRA Entrez, Source | endothelin receptor type A | 18830 | -0.212 | -0.0175 | No |
| 24 | NPY1R | NA | NPY1R Entrez, Source | neuropeptide Y receptor Y1 | 20294 | -0.354 | -0.0518 | No |
| 25 | CCL13 | NA | CCL13 Entrez, Source | chemokine (C-C motif) ligand 13 | 20652 | -0.399 | -0.0431 | No |
| 26 | BDKRB2 | NA | BDKRB2 Entrez, Source | bradykinin receptor B2 | 21108 | -0.469 | -0.0342 | No |
| 27 | NTSR1 | NA | NTSR1 Entrez, Source | neurotensin receptor 1 (high affinity) | 24807 | -1.347 | -0.0962 | No |
| 28 | OXTR | NA | OXTR Entrez, Source | oxytocin receptor | 24892 | -1.376 | -0.0243 | No |
| 29 | HTR7 | NA | HTR7 Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled) | 26240 | -2.081 | 0.0399 | No |
