Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | MODULE_311 |
| Enrichment Score (ES) | 0.5902796 |
| Normalized Enrichment Score (NES) | 1.8159978 |
| Nominal p-value | 0.0017985612 |
| FDR q-value | 0.028825933 |
| FWER p-Value | 0.105 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TNC | NA | TNC Entrez, Source | tenascin C (hexabrachion) | 258 | 3.160 | 0.2383 | Yes |
| 2 | RLBP1 | NA | RLBP1 Entrez, Source | retinaldehyde binding protein 1 | 578 | 2.692 | 0.4376 | Yes |
| 3 | SLC2A3 | NA | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 1145 | 2.212 | 0.5903 | Yes |
| 4 | HSP90B1 | NA | HSP90B1 Entrez, Source | heat shock protein 90kDa beta (Grp94), member 1 | 4925 | 0.760 | 0.5115 | No |
| 5 | UCP1 | NA | UCP1 Entrez, Source | uncoupling protein 1 (mitochondrial, proton carrier) | 9987 | 0.179 | 0.3402 | No |
| 6 | ALOX5AP | NA | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 12698 | 0.064 | 0.2460 | No |
| 7 | TCN1 | NA | TCN1 Entrez, Source | transcobalamin I (vitamin B12 binding protein, R binder family) | 12873 | 0.058 | 0.2442 | No |
| 8 | LCN2 | NA | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 12922 | 0.056 | 0.2468 | No |
| 9 | SLC2A5 | NA | SLC2A5 Entrez, Source | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 13418 | 0.037 | 0.2316 | No |
| 10 | PPBP | NA | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 13740 | 0.024 | 0.2218 | No |
| 11 | AMBP | NA | AMBP Entrez, Source | alpha-1-microglobulin/bikunin precursor | 15999 | -0.060 | 0.1438 | No |
| 12 | VWF | NA | VWF Entrez, Source | von Willebrand factor | 17158 | -0.108 | 0.1099 | No |
| 13 | SLC25A16 | NA | SLC25A16 Entrez, Source | solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 | 20595 | -0.392 | 0.0148 | No |
| 14 | UCP2 | NA | UCP2 Entrez, Source | uncoupling protein 2 (mitochondrial, proton carrier) | 21073 | -0.463 | 0.0336 | No |
| 15 | AKR1C1 | NA | AKR1C1 Entrez, Source | aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) | 22616 | -0.758 | 0.0365 | No |
| 16 | FTH1 | NA | FTH1 Entrez, Source | ferritin, heavy polypeptide 1 | 23032 | -0.845 | 0.0876 | No |
| 17 | SLC25A5 | NA | SLC25A5 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 23242 | -0.890 | 0.1496 | No |
