Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | MODULE_330 |
| Enrichment Score (ES) | 0.51212335 |
| Normalized Enrichment Score (NES) | 1.8051871 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.029143548 |
| FWER p-Value | 0.121 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SSPN | NA | SSPN Entrez, Source | sarcospan (Kras oncogene-associated gene) | 180 | 3.298 | 0.1296 | Yes |
| 2 | CRYAB | NA | CRYAB Entrez, Source | crystallin, alpha B | 203 | 3.264 | 0.2635 | Yes |
| 3 | GJA1 | NA | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 814 | 2.462 | 0.3428 | Yes |
| 4 | GSN | NA | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 1877 | 1.789 | 0.3778 | Yes |
| 5 | CACNG1 | NA | CACNG1 Entrez, Source | calcium channel, voltage-dependent, gamma subunit 1 | 1921 | 1.765 | 0.4491 | Yes |
| 6 | CALD1 | NA | CALD1 Entrez, Source | caldesmon 1 | 2095 | 1.680 | 0.5121 | Yes |
| 7 | VIPR1 | NA | VIPR1 Entrez, Source | vasoactive intestinal peptide receptor 1 | 5757 | 0.569 | 0.4015 | No |
| 8 | MYL3 | NA | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 9348 | 0.211 | 0.2787 | No |
| 9 | PLN | NA | PLN Entrez, Source | phospholamban | 10248 | 0.167 | 0.2527 | No |
| 10 | HRC | NA | HRC Entrez, Source | histidine rich calcium binding protein | 10320 | 0.164 | 0.2569 | No |
| 11 | ACTC1 | NA | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 11135 | 0.126 | 0.2323 | No |
| 12 | TRDN | NA | TRDN Entrez, Source | triadin | 11470 | 0.111 | 0.2246 | No |
| 13 | KCNA1 | NA | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 12134 | 0.085 | 0.2039 | No |
| 14 | CKMT2 | NA | CKMT2 Entrez, Source | creatine kinase, mitochondrial 2 (sarcomeric) | 13511 | 0.033 | 0.1548 | No |
| 15 | NOS1 | NA | NOS1 Entrez, Source | nitric oxide synthase 1 (neuronal) | 14403 | 0.001 | 0.1222 | No |
| 16 | TMSB4Y | NA | TMSB4Y Entrez, Source | thymosin, beta 4, Y-linked | 16657 | -0.087 | 0.0433 | No |
| 17 | FKBP1B | NA | FKBP1B Entrez, Source | FK506 binding protein 1B, 12.6 kDa | 16827 | -0.094 | 0.0410 | No |
| 18 | CXCL12 | NA | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 17216 | -0.111 | 0.0314 | No |
| 19 | CLCN1 | NA | CLCN1 Entrez, Source | chloride channel 1, skeletal muscle (Thomsen disease, autosomal dominant) | 18013 | -0.154 | 0.0086 | No |
| 20 | GJA5 | NA | GJA5 Entrez, Source | gap junction protein, alpha 5, 40kDa (connexin 40) | 18191 | -0.165 | 0.0089 | No |
| 21 | RYR1 | NA | RYR1 Entrez, Source | ryanodine receptor 1 (skeletal) | 18403 | -0.178 | 0.0085 | No |
| 22 | FXYD1 | NA | FXYD1 Entrez, Source | FXYD domain containing ion transport regulator 1 (phospholemman) | 18692 | -0.201 | 0.0063 | No |
| 23 | ACTA1 | NA | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 18963 | -0.223 | 0.0056 | No |
| 24 | GNAO1 | NA | GNAO1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 23419 | -0.930 | -0.1192 | No |
| 25 | DSTN | NA | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 23829 | -1.045 | -0.0910 | No |
| 26 | OXTR | NA | OXTR Entrez, Source | oxytocin receptor | 24892 | -1.376 | -0.0731 | No |
| 27 | FLII | NA | FLII Entrez, Source | flightless I homolog (Drosophila) | 26059 | -1.955 | -0.0351 | No |
| 28 | CHRNB1 | NA | CHRNB1 Entrez, Source | cholinergic receptor, nicotinic, beta 1 (muscle) | 26089 | -1.976 | 0.0454 | No |
