Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | MODULE_362 |
| Enrichment Score (ES) | -0.5429494 |
| Normalized Enrichment Score (NES) | -1.6665716 |
| Nominal p-value | 0.002057613 |
| FDR q-value | 0.09500621 |
| FWER p-Value | 0.415 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | JAG1 | NA | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 130 | 3.400 | 0.0945 | No |
| 2 | EPAS1 | NA | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 867 | 2.416 | 0.1381 | No |
| 3 | PBX3 | NA | PBX3 Entrez, Source | pre-B-cell leukemia transcription factor 3 | 2238 | 1.620 | 0.1352 | No |
| 4 | NRG1 | NA | NRG1 Entrez, Source | neuregulin 1 | 3117 | 1.271 | 0.1402 | No |
| 5 | MFNG | NA | MFNG Entrez, Source | manic fringe homolog (Drosophila) | 4627 | 0.832 | 0.1092 | No |
| 6 | MMP19 | NA | MMP19 Entrez, Source | matrix metallopeptidase 19 | 4837 | 0.779 | 0.1243 | No |
| 7 | FGF1 | NA | FGF1 Entrez, Source | fibroblast growth factor 1 (acidic) | 6501 | 0.453 | 0.0766 | No |
| 8 | IL18 | NA | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 14572 | -0.005 | -0.2187 | No |
| 9 | FGF6 | NA | FGF6 Entrez, Source | fibroblast growth factor 6 | 14709 | -0.010 | -0.2234 | No |
| 10 | IL8 | NA | IL8 Entrez, Source | interleukin 8 | 15907 | -0.056 | -0.2656 | No |
| 11 | T | NA | T Entrez, Source | T, brachyury homolog (mouse) | 15909 | -0.056 | -0.2640 | No |
| 12 | FGF2 | NA | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 20293 | -0.354 | -0.4142 | No |
| 13 | KDR | NA | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 22433 | -0.714 | -0.4717 | No |
| 14 | FIGF | NA | FIGF Entrez, Source | c-fos induced growth factor (vascular endothelial growth factor D) | 23302 | -0.902 | -0.4771 | No |
| 15 | PTPRR | NA | PTPRR Entrez, Source | protein tyrosine phosphatase, receptor type, R | 25101 | -1.465 | -0.5002 | Yes |
| 16 | TNFSF12 | NA | TNFSF12 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 12 | 25648 | -1.710 | -0.4702 | Yes |
| 17 | ANPEP | NA | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 26355 | -2.176 | -0.4325 | Yes |
| 18 | NRP1 | NA | NRP1 Entrez, Source | neuropilin 1 | 26913 | -2.831 | -0.3703 | Yes |
| 19 | TNFAIP2 | NA | TNFAIP2 Entrez, Source | tumor necrosis factor, alpha-induced protein 2 | 27266 | -4.266 | -0.2586 | Yes |
| 20 | VEGFC | NA | VEGFC Entrez, Source | vascular endothelial growth factor C | 27284 | -4.454 | -0.1292 | Yes |
| 21 | ANGPT1 | NA | ANGPT1 Entrez, Source | angiopoietin 1 | 27287 | -4.480 | 0.0015 | Yes |
