Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 1 |
| GeneSet | MODULE_573 |
| Enrichment Score (ES) | 0.6852295 |
| Normalized Enrichment Score (NES) | 1.7585143 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.050181456 |
| FWER p-Value | 0.214 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CDKN2C | NA | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 93 | 3.507 | 0.1355 | Yes |
| 2 | TNC | NA | TNC Entrez, Source | tenascin C (hexabrachion) | 258 | 3.160 | 0.2546 | Yes |
| 3 | RLBP1 | NA | RLBP1 Entrez, Source | retinaldehyde binding protein 1 | 578 | 2.692 | 0.3495 | Yes |
| 4 | GADD45A | NA | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 793 | 2.479 | 0.4399 | Yes |
| 5 | KAT2B | NA | 918 | 2.376 | 0.5294 | Yes | ||
| 6 | SLC2A3 | NA | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 1145 | 2.212 | 0.6088 | Yes |
| 7 | CDKN1C | NA | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 1317 | 2.089 | 0.6852 | Yes |
| 8 | CDKN1A | NA | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3168 | 1.250 | 0.6670 | No |
| 9 | HSP90B1 | NA | HSP90B1 Entrez, Source | heat shock protein 90kDa beta (Grp94), member 1 | 4925 | 0.760 | 0.6328 | No |
| 10 | CDKN2A | NA | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 5692 | 0.579 | 0.6277 | No |
| 11 | GMNN | NA | GMNN Entrez, Source | geminin, DNA replication inhibitor | 9099 | 0.224 | 0.5118 | No |
| 12 | UCP1 | NA | UCP1 Entrez, Source | uncoupling protein 1 (mitochondrial, proton carrier) | 9987 | 0.179 | 0.4864 | No |
| 13 | SESN2 | NA | SESN2 Entrez, Source | sestrin 2 | 10062 | 0.176 | 0.4907 | No |
| 14 | TBRG4 | NA | TBRG4 Entrez, Source | transforming growth factor beta regulator 4 | 11863 | 0.095 | 0.4285 | No |
| 15 | ALOX5AP | NA | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 12698 | 0.064 | 0.4005 | No |
| 16 | LCN2 | NA | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 12922 | 0.056 | 0.3946 | No |
| 17 | SLC2A5 | NA | SLC2A5 Entrez, Source | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 13418 | 0.037 | 0.3779 | No |
| 18 | PPBP | NA | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 13740 | 0.024 | 0.3671 | No |
| 19 | AMBP | NA | AMBP Entrez, Source | alpha-1-microglobulin/bikunin precursor | 15999 | -0.060 | 0.2868 | No |
| 20 | VWF | NA | VWF Entrez, Source | von Willebrand factor | 17158 | -0.108 | 0.2487 | No |
| 21 | SLC25A16 | NA | SLC25A16 Entrez, Source | solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 | 20595 | -0.392 | 0.1383 | No |
| 22 | UCP2 | NA | UCP2 Entrez, Source | uncoupling protein 2 (mitochondrial, proton carrier) | 21073 | -0.463 | 0.1392 | No |
| 23 | CDKN3 | NA | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 21570 | -0.547 | 0.1427 | No |
| 24 | MYC | NA | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 25669 | -1.721 | 0.0608 | No |
