Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls #wt_versus_radiation.mainSample.cls #wt_versus_radiation_repos |
| Phenotype | mainSample.cls#wt_versus_radiation_repos |
| Upregulated in class | 2 |
| GeneSet | HINATA_NFKB_IMMU_INF |
| Enrichment Score (ES) | -0.52861446 |
| Normalized Enrichment Score (NES) | -1.2031374 |
| Nominal p-value | 0.25454545 |
| FDR q-value | 0.24585907 |
| FWER p-Value | 0.917 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PTX3 | NA | PTX3 Entrez, Source | pentraxin-related gene, rapidly induced by IL-1 beta | 227 | 3.226 | 0.1652 | No |
| 2 | IL6 | NA | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 4216 | 0.927 | 0.0691 | No |
| 3 | NFKBIA | NA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 6294 | 0.482 | 0.0190 | No |
| 4 | CCL2 | NA | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 9704 | 0.193 | -0.0955 | No |
| 5 | CXCL6 | NA | CXCL6 Entrez, Source | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 12156 | 0.084 | -0.1807 | No |
| 6 | CCL20 | NA | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 12374 | 0.076 | -0.1845 | No |
| 7 | OLR1 | NA | OLR1 Entrez, Source | oxidised low density lipoprotein (lectin-like) receptor 1 | 12589 | 0.068 | -0.1887 | No |
| 8 | IL8 | NA | IL8 Entrez, Source | interleukin 8 | 15907 | -0.056 | -0.3072 | No |
| 9 | NFKB1 | NA | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 21956 | -0.621 | -0.4952 | Yes |
| 10 | CD83 | NA | CD83 Entrez, Source | CD83 molecule | 22644 | -0.763 | -0.4793 | Yes |
| 11 | IL1B | NA | IL1B Entrez, Source | interleukin 1, beta | 22830 | -0.802 | -0.4429 | Yes |
| 12 | RELA | NA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 23495 | -0.950 | -0.4161 | Yes |
| 13 | CXCL3 | NA | CXCL3 Entrez, Source | chemokine (C-X-C motif) ligand 3 | 24820 | -1.350 | -0.3920 | Yes |
| 14 | CXCL2 | NA | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 24873 | -1.368 | -0.3203 | Yes |
| 15 | ICAM1 | NA | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 25105 | -1.467 | -0.2498 | Yes |
| 16 | IRF1 | NA | IRF1 Entrez, Source | interferon regulatory factor 1 | 25960 | -1.890 | -0.1794 | Yes |
| 17 | TNFAIP2 | NA | TNFAIP2 Entrez, Source | tumor necrosis factor, alpha-induced protein 2 | 27266 | -4.266 | 0.0023 | Yes |
