Datasetexpression_mean_normalized_with_dChip_geneAvg_Mar1014_PNs.mainSample.cls
#wt_versus_radiation.mainSample.cls
#wt_versus_radiation_repos
PhenotypemainSample.cls#wt_versus_radiation_repos
Upregulated in class1
GeneSetNRL_DN.V1_DN
Enrichment Score (ES)0.38181317
Normalized Enrichment Score (NES)1.4905564
Nominal p-value0.0020283975
FDR q-value0.036472324
FWER p-Value0.284
Table: GSEA Results Summary



Fig 1: Enrichment plot: NRL_DN.V1_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1HES5NAHES5
Entrez,  Source
hairy and enhancer of split 5 (Drosophila)74.0260.0307Yes
2IL17DNAIL17D
Entrez,  Source
interleukin 17D1273.4070.0525Yes
3FABP7NAFABP7
Entrez,  Source
fatty acid binding protein 7, brain3233.0440.0687Yes
4SLC8A3NASLC8A3
Entrez,  Source
solute carrier family 8 (sodium-calcium exchanger), member 35122.7810.0831Yes
5PLEKHH2NAPLEKHH2
Entrez,  Source
pleckstrin homology domain containing, family H (with MyTH4 domain) member 26262.6490.0993Yes
6GTF2INAGTF2I
Entrez,  Source
general transcription factor II, i6892.5870.1169Yes
7JAM3NAJAM3
Entrez,  Source
junctional adhesion molecule 36962.5800.1365Yes
8TNPO2NATNPO2
Entrez,  Source
transportin 2 (importin 3, karyopherin beta 2b)7292.5440.1549Yes
9FKBP9NAFKBP9
Entrez,  Source
FK506 binding protein 9, 63 kDa8032.4670.1711Yes
10KIF5CNAKIF5C
Entrez,  Source
kinesin family member 5C10922.2480.1778Yes
11METRNNAMETRN
Entrez,  Source
meteorin, glial cell differentiation regulator13702.0590.1835Yes
12BST2NABST2
Entrez,  Source
bone marrow stromal cell antigen 214302.0170.1968Yes
13DPP8NADPP8
Entrez,  Source
dipeptidyl-peptidase 814811.9890.2102Yes
14C14orf132NAC14ORF132
Entrez,  Source
chromosome 14 open reading frame 13215821.9320.2214Yes
15BAXNABAX
Entrez,  Source
BCL2-associated X protein18231.8100.2265Yes
16PTPN13NAPTPN13
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)18291.8090.2402Yes
17GGT7NA18661.7950.2526Yes
18U2AF1NAU2AF1
Entrez,  Source
U2 small nuclear RNA auxiliary factor 120781.6860.2578Yes
19MAP6NAMAP6
Entrez,  Source
microtubule-associated protein 622631.6110.2634Yes
20PDE1CNAPDE1C
Entrez,  Source
phosphodiesterase 1C, calmodulin-dependent 70kDa22861.6010.2749Yes
21DIXDC1NADIXDC1
Entrez,  Source
DIX domain containing 123251.5850.2857Yes
22HRASLSNAHRASLS
Entrez,  Source
HRAS-like suppressor24731.5160.2919Yes
23ERMAPNAERMAP
Entrez,  Source
erythroblast membrane-associated protein (Scianna blood group)26231.4510.2976Yes
24ABHD3NAABHD3
Entrez,  Source
abhydrolase domain containing 326721.4360.3069Yes
25ELOVL2NAELOVL2
Entrez,  Source
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 227591.3960.3144Yes
26EN2NAEN2
Entrez,  Source
engrailed homolog 229391.3340.3181Yes
27GPR124NAGPR124
Entrez,  Source
G protein-coupled receptor 12430801.2840.3228Yes
28INPPL1NAINPPL1
Entrez,  Source
inositol polyphosphate phosphatase-like 132121.2360.3275Yes
29ST3GAL3NAST3GAL3
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 332371.2300.3360Yes
30RAB8ANARAB8A
Entrez,  Source
RAB8A, member RAS oncogene family34501.1680.3372Yes
31TTLL1NATTLL1
Entrez,  Source
tubulin tyrosine ligase-like family, member 135321.1440.3430Yes
32ECE1NAECE1
Entrez,  Source
endothelin converting enzyme 135421.1400.3515Yes
33FAM134CNA35711.1300.3591Yes
34WDR31NAWDR31
Entrez,  Source
WD repeat domain 3137001.0830.3627Yes
35GREB1NAGREB1
Entrez,  Source
-37621.0650.3687Yes
36SLC7A3NASLC7A3
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 338961.0200.3716Yes
37MOGAT1NAMOGAT1
Entrez,  Source
monoacylglycerol O-acyltransferase 139910.9890.3757Yes
38DFNA5NADFNA5
Entrez,  Source
deafness, autosomal dominant 541980.9320.3753Yes
39DNAJC9NADNAJC9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily C, member 946060.8410.3668Yes
40MFNGNAMFNG
Entrez,  Source
manic fringe homolog (Drosophila)46270.8320.3725Yes
41SLC25A13NASLC25A13
Entrez,  Source
solute carrier family 25, member 13 (citrin)46570.8240.3778Yes
42SALL3NASALL3
Entrez,  Source
sal-like 3 (Drosophila)47160.8060.3818Yes
43TOM1L2NATOM1L2
Entrez,  Source
target of myb1-like 2 (chicken)53060.6600.3652No
44NOXO1NANOXO1
Entrez,  Source
NADPH oxidase organizer 155400.6090.3613No
45ALDH2NAALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)56190.5940.3630No
46BMP5NABMP5
Entrez,  Source
bone morphogenetic protein 561010.5110.3493No
47RNF25NARNF25
Entrez,  Source
ring finger protein 2565740.4440.3353No
48PRMT1NAPRMT1
Entrez,  Source
protein arginine methyltransferase 168330.4150.3290No
49D4S234ENAD4S234E
Entrez,  Source
-68560.4120.3314No
50MYOCDNAMYOCD
Entrez,  Source
myocardin70140.3960.3287No
51RNASE4NARNASE4
Entrez,  Source
ribonuclease, RNase A family, 478710.3110.2996No
52TMED9NATMED9
Entrez,  Source
transmembrane emp24 protein transport domain containing 984640.2650.2799No
53PIK3AP1NAPIK3AP1
Entrez,  Source
phosphoinositide-3-kinase adaptor protein 185070.2630.2803No
54BMP15NABMP15
Entrez,  Source
bone morphogenetic protein 1586820.2500.2759No
55C11orf52NAC11ORF52
Entrez,  Source
chromosome 11 open reading frame 5287180.2470.2765No
56ABCC9NAABCC9
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 987660.2430.2766No
57SMPDL3ANASMPDL3A
Entrez,  Source
sphingomyelin phosphodiesterase, acid-like 3A89190.2340.2728No
58ARPC3NAARPC3
Entrez,  Source
actin related protein 2/3 complex, subunit 3, 21kDa89660.2320.2729No
59CCKBRNACCKBR
Entrez,  Source
cholecystokinin B receptor94210.2070.2578No
60TC2NNA96270.1960.2518No
61CCL2NACCL2
Entrez,  Source
chemokine (C-C motif) ligand 297040.1930.2505No
62PECAM1NAPECAM1
Entrez,  Source
platelet/endothelial cell adhesion molecule (CD31 antigen)100990.1740.2373No
63CNGB3NACNGB3
Entrez,  Source
cyclic nucleotide gated channel beta 3104130.1600.2271No
64PARVGNAPARVG
Entrez,  Source
parvin, gamma105350.1540.2238No
65BSPRYNABSPRY
Entrez,  Source
B-box and SPRY domain containing105650.1530.2239No
66CPLX2NACPLX2
Entrez,  Source
complexin 2107260.1450.2191No
67ABCB4NAABCB4
Entrez,  Source
ATP-binding cassette, sub-family B (MDR/TAP), member 4107500.1440.2194No
68ATP2A1NAATP2A1
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1116890.1020.1857No
69GABRA2NAGABRA2
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, alpha 2120360.0890.1736No
70EYA1NAEYA1
Entrez,  Source
eyes absent homolog 1 (Drosophila)121350.0850.1707No
71TRIM17NATRIM17
Entrez,  Source
tripartite motif-containing 17130610.0510.1371No
72SLAMF9NASLAMF9
Entrez,  Source
SLAM family member 9132730.0420.1297No
73RASGRF2NARASGRF2
Entrez,  Source
Ras protein-specific guanine nucleotide-releasing factor 2140230.0140.1022No
74SUPT16HNASUPT16H
Entrez,  Source
suppressor of Ty 16 homolog (S. cerevisiae)14514-0.0030.0842No
75DPRXNADPRX
Entrez,  Source
divergent-paired related homeobox14549-0.0040.0830No
76GLRA3NAGLRA3
Entrez,  Source
glycine receptor, alpha 314944-0.0190.0687No
77CALCANACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha15001-0.0210.0668No
78TSPAN33NATSPAN33
Entrez,  Source
tetraspanin 3315029-0.0220.0660No
79AP2B1NAAP2B1
Entrez,  Source
adaptor-related protein complex 2, beta 1 subunit15912-0.0560.0340No
80PDIA3NAPDIA3
Entrez,  Source
protein disulfide isomerase family A, member 316486-0.0800.0135No
81GJD2NA16754-0.0910.0044No
82DYNC1LI1NADYNC1LI1
Entrez,  Source
dynein, cytoplasmic 1, light intermediate chain 117511-0.125-0.0224No
83GLRA1NAGLRA1
Entrez,  Source
glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)17569-0.128-0.0235No
84DYSFNADYSF
Entrez,  Source
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)18409-0.179-0.0530No
85GZMMNAGZMM
Entrez,  Source
granzyme M (lymphocyte met-ase 1)18821-0.212-0.0665No
86LMNB2NALMNB2
Entrez,  Source
lamin B219005-0.227-0.0715No
87USP25NAUSP25
Entrez,  Source
ubiquitin specific peptidase 2519091-0.234-0.0728No
88ZNF316NAZNF316
Entrez,  Source
zinc finger protein 31619119-0.237-0.0720No
89ORAI1NA19195-0.244-0.0729No
90BBXNABBX
Entrez,  Source
bobby sox homolog (Drosophila)19336-0.254-0.0761No
91CDT1NACDT1
Entrez,  Source
chromatin licensing and DNA replication factor 119361-0.256-0.0750No
92ZNF146NAZNF146
Entrez,  Source
zinc finger protein 14619505-0.270-0.0782No
93CLIC4NACLIC4
Entrez,  Source
chloride intracellular channel 419546-0.275-0.0775No
94PRDM1NAPRDM1
Entrez,  Source
PR domain containing 1, with ZNF domain20217-0.343-0.0995No
95CLCA3PNA20274-0.352-0.0989No
96CRYBG3NA20471-0.377-0.1032No
97NR4A1NANR4A1
Entrez,  Source
nuclear receptor subfamily 4, group A, member 120585-0.391-0.1043No
98RXRGNARXRG
Entrez,  Source
retinoid X receptor, gamma20994-0.451-0.1159No
99SOCS3NASOCS3
Entrez,  Source
suppressor of cytokine signaling 321067-0.462-0.1150No
100ATOH7NAATOH7
Entrez,  Source
atonal homolog 7 (Drosophila)21128-0.472-0.1135No
101CASP7NACASP7
Entrez,  Source
caspase 7, apoptosis-related cysteine peptidase21218-0.483-0.1131No
102RGS20NARGS20
Entrez,  Source
regulator of G-protein signalling 2021414-0.518-0.1163No
103RASA2NARASA2
Entrez,  Source
RAS p21 protein activator 221520-0.538-0.1160No
104ACBD6NAACBD6
Entrez,  Source
acyl-Coenzyme A binding domain containing 621534-0.540-0.1124No
105NFKB1NANFKB1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)21956-0.621-0.1231No
106CLIC1NACLIC1
Entrez,  Source
chloride intracellular channel 122393-0.706-0.1337No
107C19orf39NAC19ORF39
Entrez,  Source
chromosome 19 open reading frame 3922475-0.723-0.1311No
108ATE1NAATE1
Entrez,  Source
arginyltransferase 122915-0.822-0.1409No
109CTBSNACTBS
Entrez,  Source
chitobiase, di-N-acetyl-23125-0.863-0.1420No
110CTHNACTH
Entrez,  Source
cystathionase (cystathionine gamma-lyase)23517-0.956-0.1490No
111PRKCQNAPRKCQ
Entrez,  Source
protein kinase C, theta23978-1.082-0.1576No
112TRAPPC3NATRAPPC3
Entrez,  Source
trafficking protein particle complex 324297-1.178-0.1602No
113ARHGDIBNAARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta24415-1.214-0.1552No
114RGL3NARGL3
Entrez,  Source
ral guanine nucleotide dissociation stimulator-like 324562-1.267-0.1509No
115MPP6NAMPP6
Entrez,  Source
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)24804-1.345-0.1494No
116ELK3NAELK3
Entrez,  Source
ELK3, ETS-domain protein (SRF accessory protein 2)25026-1.430-0.1465No
117EPM2AIP1NAEPM2AIP1
Entrez,  Source
EPM2A (laforin) interacting protein 125207-1.505-0.1416No
118CLPBNACLPB
Entrez,  Source
ClpB caseinolytic peptidase B homolog (E. coli)25852-1.827-0.1512No
119QSOX1NA26171-2.043-0.1472No
120RNF149NARNF149
Entrez,  Source
ring finger protein 14926232-2.076-0.1335No
121HARS2NAHARS2
Entrez,  Source
histidyl-tRNA synthetase 226331-2.153-0.1205No
122TMEM158NATMEM158
Entrez,  Source
transmembrane protein 15826610-2.396-0.1124No
123MOXD1NAMOXD1
Entrez,  Source
monooxygenase, DBH-like 126683-2.480-0.0960No
124ADRB1NAADRB1
Entrez,  Source
adrenergic, beta-1-, receptor26938-2.889-0.0831No
125WWC1NAWWC1
Entrez,  Source
WW, C2 and coiled-coil domain containing 126975-2.960-0.0617No
126MINANAMINA
Entrez,  Source
MYC induced nuclear antigen27005-3.051-0.0393No
127TUFT1NATUFT1
Entrez,  Source
tuftelin 127042-3.161-0.0164No
128ADRB2NAADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface27138-3.5000.0070No
Table: GSEA details [plain text format]



Fig 2: NRL_DN.V1_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NRL_DN.V1_DN: Random ES distribution   
Gene set null distribution of ES for NRL_DN.V1_DN